6 LJP patients. Total of 20 deep periodontal pockets & 10 normal periodontal sites. Tx consisted of 3 stages over a period of 22 weeks. Results of tx were monitored for an additional 38 weeks.
Use of tetracycline was suggested for one more week after obtaining negative cultures = 3 weeks to prevent reappearance of AA.
AA as etiologic agent in LJP.
Effective therapy can be monitored by subgingival AA counts.
"Tetracycline therapy should be included in the Tx of LJP at least in cases treated without surgery". wise healthy adolescent, which is characterized by rapid loss of alveolar bone about more than one tooth of the permanent dentition. There are two basic forms in which it occurs. In one form of the disease, the only teeth affected are the first molars and incisors. In the order, more generalized form, it may affect most of the dentition. The amount of destruction manifested is not commensurate with the amount of local irritants present ".
The prevalence of the disease varies from zero, for those who do not believe in the existence of such an entity, to 15% of all periodontal disorders. This large variation is explained by the different definition of this entity.
The onset of the disease is insidious and occurs sometime between the ages of 11 and 13. It has been consistently reported that this disease affects more females than males, and that there is a familial tendency for this disease. In the vast majority of cases of periodontosis, the amount of periodontal destruction observed is not commensurate with the amount of local irritants which can be found.
Radiographically, the common pattern of bone loss is usually described as an arc shaped loss of alveolar bone extending from the distal surface of the second bicuspid to the mesial surface of the second molar; the incisors are also usually involved.
The progression of the disease is faster than in adult periodontitis, and the primary teeth are not affected or prematurely exfoliated erial penetration of the periodontium in juvenile periodontitis. They took biopsy material during flap surgery to the lower incisors. The transmission electron microscopic observation revealed bacteria, largely Gram-negative, widespread in the soft tissue close to the gingival crest as well as at deeper levels. They described PMNs in association with bacteria, and some PMNs showed phagocytosis of bacteria without degranulation.
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