Gilbert AD, Lloyd Ch, Scrimgeour SN. The effect of a light-cured periodontal dressing material on HeLa cells and fibroblasts in vitro. J Periodontol, 65: 324-9, 1994.

The effect that a visible light curing periodontal dressing material based upon a urethane dimethacrylate resin has upon HeLa cells and fibroblasts in its uncured and fully cured state has been examined in vitro.

Results

• Fully cured material has no effect on either cell type.
• Uncured material produces a surrounding zone of growth inhibition and cell death on direct contact.
• Unhibition is caused by the release into the medium of substances toxic to cells. However, this growth inhibition is overcome in time (5 days). It is suggested that partly cured material containing residual free monomer in contact with a healing gingival site could impede rapid repair. Nuclear magnetic resonance microimaging has shown that in places where there is a greater depth of material (interproximal regions) this material may be partly cured.
• Increasing the exposure to the curing light will prevent (or minimize) the presence of partly cured material; the fully material being compatible with the cells.

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