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DELIVERY BY IRRIGATION
Silverstein, Bissad, Manouchehr-Pour and Greenwell: Clinical and
Microbioogical Effects of Local Tetracycline Irrigation On Periodontics.
J Perio, 59:301, 1988.
Purpose:
The purpose of this study was to compare the effect of scaling and root planing (SC/RP) alone and tetracycline irrigation alone on the clinical and microbiologic parameters of diseased periodontal pockets.
Materials and methods:
A total of 7 patients with moderate periodontitis were included in this study.
One tooth from each quadrant was selected for one of the following treatments groups; no treatment, saline irrigation, tetracycline irrigation, SC/RP. Plaque index, gingival index, probing depth, bleeding on probing (BOP, and gingival fluid were recorded. Also samples were examined under dark-field microscope.
Results:
TCN and SC/RP resulted in significant improvement in gingival index and bleeding time. Gingival fluid flow decreased for TCN and SC/RP only. This was significant for SC/RP at week 4. BOP showed improvement at week four for TCN and weeks 4 and 8 for SC/RP. Probing depths reported no change.
Microbiologic indicators showed coccoid cell increase for TCN and SC/RP at 2, 4, and 8 weeks. Motile rods decrease for TCN and SC/RP at 2, 4, and 8 weeks. Spirochetes decrease at 2, 4, and 8 weeks.
Conclusion:
The tetracycline and SC/RP are equally effective in the alterations in the subgingival microflora and improvement in the clinical index
Tetracycline irrigation without prior SC/RP has an effect similar to that of SC/RP alone in converting a disease-associated subgingival flora to healthy state.
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