Literature Review | Chemotherapeutics
[PREVIOUS] | [NEXT]

ANTIMICROBIALS: RINSES

Wolff, LF., Philstrom, BL., Bakdash, MB., Schaffer, EM., Aeppli, DM., and CL Bandt : Four Year Investigation of Salt and Peroxide Regimen compared with Conventional Oral Hygiene. JADA 118:67, 1989.

Purpose:

The purposes of this 4 year investigation were: compare the effectiveness of patient applied sodium bicarbonate, hydrogen peroxide, and sodium chloride to the use of conventional oral hygiene methods on the clinical measures of periodontal disease: and to evaluate the compliance and acceptance of these two regimens.

Materials and Methods:

347 subjects were randomly divided in to the two groups. A total of 171 of these subjects completed the four year study. Group 1: conventional oral hygiene, soft brush, sulcular method (n=87). Group 2: Salt and peroxide regimen (n=84). Each subject mixed sodium bicarbonate with hydrogen peroxide to form a paste. This paste was applied with a soft tooth brush and rubber tip for at least a minute. Floss was then used. After the floss, an irrigating device was used with NaCl or magnesium sulfate (Epsom salt) for patients with HTN. Eight teeth were evaluated (six of these were the Ramfjord teeth). Plaque index (PI), gingival index (GI), and probing depths were recorded by the investigators. Compliance was determined by a self-administered questionnaire.

Results:

By 48 months, the plaque index had returned to baseline in both groups. At 8 and 24 months the conventional group had significant improvement, and at 16 months the S/P group had significant improvement. The 2 study groups had significant reductions in the PD at 8,16,24 and 48 months when compared to baseline. Even when the data was broken down according to probing depths and compilers vs. non compilers there were no differences between the groups.

Conclusion:

There was no difference between the salt and peroxide and the conventional oral hygiene regimens with respect to clinical measurements in individuals with mild or moderate periodontitis.
Back: Chemotherapeutic Articles
Menu: Literature Review Topics
Home: PIC Homepage

PERIODONTICS INFORMATION CENTER