Periodontology Literature Review

CHLORHEXIDINE

Addy, M. and L. Hunter. The Effects of a 0.2% chlorhexidine gluconate mouthrinse on plaque, tooth staining, and candida in aphtous ulcer patients. A double-blind placebo-controlled cross-over study. J. . Periodontol., 14:267;1987.

Purpose:

This study was designed to test several ideas in regards to chlorhexidine. The first of which was to evaluate the plaque fighting abilities of chlorhexidine in a quantitative way alone with a quantitative look at the staining of teeth during the use of chlorhexidine. These authors report that until this time that no other investigators have done such a quantitative evaluation for staining but only reported staining in subjective terms. Finally this study was designed to evaluate chlorhexidinešs candida fighting properties.

Materials and methods:

The authors have chosen to use 40 mild-apthous ulcer patients in a 15 week with and without chlorhexidine study. The patients daily hygiene regime was unsupervised and the chlorhexidine or placebo mouthrinse was used three times daily.

Results:

The results showed that the chlorhexidine treatment decreased the recorded average plaque index for both buccal and lingual surfaces. The plaque distributions indicated tooth brushing behavior to be a related component. Staining was significantly increased with chlorhexidine use and its removal was complete with professional hygiene only. The number of patients with Candida at the baseline was 5, which makes this study not an ideal one for the evaluation and elucidation of changes for Candida effects from chlorhexidine.

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